Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384671 | 0.85 | TPMT (0.58) | TPMTLMNAMAPK1HSD17B10CA12 | |
| SCHEMBL12013947 | 0.79 | LMNA (0.48) | TPMTLMNAMAPK1HTTRAB9A | |
| SCHEMBL2183846 | 0.79 | CES2 (0.48) | TPMTLMNAMAPK1HTTRAB9A | |
| SCHEMBL23817375 | 0.79 | TPMT (0.71) | TPMTLMNAMAPK1HSD17B10CA12 | |
| SCHEMBL27910659 | 0.78 | TPMT (0.50) | TPMTLMNARAB9AHSD17B10CA12 | |
| SCHEMBL6092664 | 0.78 | CA12 (0.52) | TPMTLMNAMAPK1HTTRAB9A | |
| SCHEMBL1105952 | 0.76 | HDAC1 (0.59) | TPMTLMNAMAPK1HTTRAB9A | |
| SCHEMBL7827636 | 0.76 | TPMT (0.54) | TPMTLMNAMAPK1HTTRAB9A | |
| SCHEMBL20094254 | 0.76 | TPMT (0.54) | TPMTLMNAMAPK1HSD17B10CA12 | |
| SCHEMBL1233792 | 0.76 | TPMT (0.54) | TPMTLMNAMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271340-A | Heterospiro compounds, mixtures and electroluminescent devices | 武汉华星光电半导体显示技术有限公司 | 2024-07-02 | — | — | CN | disclosed |