Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.53 |
| ▸ | LCK | P06239 | 17/20 | 0.53 |
| ▸ | EGFR | P00533 | 9/20 | 0.53 |
| ▸ | BTK | Q06187 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855214 | 0.87 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL29199693 | 0.83 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL29199692 | 0.83 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL29264612 | 0.82 | JAK3 (0.56) | JAK3LCKEGFRBTK | |
| SCHEMBL29264631 | 0.82 | JAK3 (0.66) | JAK3LCKEGFRBTK | |
| SCHEMBL31039900 | 0.81 | JAK3 (0.67) | JAK3LCKEGFRBTK | |
| SCHEMBL21946745 | 0.81 | CDK4 (0.49) | JAK3LCKEGFRBTK | |
| SCHEMBL31039885 | 0.77 | BTK (0.52) | JAK3LCKEGFRBTK | |
| SCHEMBL21855188 | 0.77 | JAK3 (0.82) | JAK3LCKEGFRBTK | |
| SCHEMBL20539779 | 0.77 | LCK (0.49) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |