Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 6/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | SELE | P16581 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419937 | 0.98 | CYP3A4 (0.47) | CYP3A4MAPTERN1SELLSELP | |
| Formaldehyde SCHEMBL28141408 | 0.96 | CYP3A4 (0.46) | CYP3A4MAPTERN1SELLSELP | |
| SCHEMBL3185655 | 0.88 | ERN1 (0.52) | CYP3A4MAPTERN1SELLSELP | |
| Benzaldehyde SCHEMBL28141406 | 0.86 | CYP2A6 (0.47) | CYP3A4MAPTERN1KDM4EALDH1A1 | |
| SCHEMBL1929437 | 0.83 | ERN1 (0.44) | CYP3A4MAPTERN1CA1CA2 | |
| SCHEMBL79252 | 0.83 | ERN1 (0.44) | CYP3A4MAPTERN1CA1CA2 | |
| SCHEMBL869070 | 0.82 | CYP3A4 (0.48) | CYP3A4MAPTERN1ACHEUSP2 | |
| SCHEMBL29169368 | 0.80 | ERN1 (0.42) | CYP3A4MAPTERN1CA1CA2 | |
| SCHEMBL11045347 | 0.80 | ERN1 (0.42) | CYP3A4MAPTERN1CA1CA2 | |
| SCHEMBL28225789 | 0.80 | ERN1 (0.42) | CYP3A4MAPTERN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691782-B2 | Active carbon, production method thereof and polarizable electrode | SHOWA DENKO K.K. (JP) | 2010-04-06 | — | — | US | claimed |
| US-20030099424-A1 | Optical gain media and methods for making and using same | MOHAJER YOUSEF (US) | 2003-05-29 | — | — | US | claimed |
| WO-2003018592-A1 | OPTICAL GAIN MEDIA | PHOTON-X, INC. (US) | 2003-03-06 | — | — | WO | claimed |
| US-4727024-A | Binding assays involving formation and detection of light scattering crystals | ARTHUR D. LITTLE, INC. | 1988-02-23 | — | — | US | claimed |
| JP-58045274-A | — | — | None | — | — | JP | disclosed |
| JP-6206771-A | — | — | None | — | — | JP | disclosed |
| JP-9052708-A | — | — | None | — | — | JP | disclosed |
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | disclosed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-3814347-B1 | NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-03 | — | — | EP | disclosed |
| CN-111592561-B | Asymmetric diimine titanium metal complex and preparation method and application thereof | 上海化工研究院有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-3866230-B1 | MULTI-LAYER STRUCTURED CARBONACEOUS MATERIAL, PROCESS FOR PRODUCING THE SAME, AND NONAQUEOUS SECONDARY BATTERY ADOPTING THE SAME | MITSUBISHI CHEM CORP (JP) | 2023-03-22 | — | — | EP | disclosed |
| US-4806141-A | 1-OXY-2-OXIMO-3-OXO-5-PHENYL CYCLOMEXENE | ICI AUSTRALIA LIMITED (AU) | 1989-02-21 | — | — | US | disclosed |
| EP-0085530-B1 | CYCLOHEXANE DIONE DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | ICI AUSTRALIA LIMITED (AU) | 1987-07-01 | — | — | EP | disclosed |
| US-4604128-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-08-05 | — | — | US | disclosed |
| EP-0177222-A1 | Cyclohexane-1,3-dione derivatives, compositions containing them, processes for preparing them, and their use as herbicides and plant growth regulators | ICI AUSTRALIA LIMITED (AU) | 1986-04-09 | — | — | EP | disclosed |
| EP-0085530-A2 | Cyclohexane dione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them | ICI AUSTRALIA LIMITED (AU) | 1983-08-10 | — | — | EP | disclosed |
| JP-S5845274-A | PREPARATION OF LEAD CORE | PILOT PRECISION CO LTD | 1983-03-16 | — | — | JP | disclosed |
| US-4226792-A | BALLISTICS PROPELLANT ADDITIVE | NL INDUSTRIES, INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4037172-A | Plastic laser materials | AMERICAN STANDARD, INC. (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | DGKZ, DGKA, DGKG | CYP3A4 4513/4885MAPT 4477/4885ERN1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.