Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264849 | 0.90 | KMT2A (0.47) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264855 | 0.89 | KMT2A (0.46) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264847 | 0.85 | KDM4E (0.50) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264860 | 0.84 | MAPK8 (0.47) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264840 | 0.82 | AR (0.50) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264868 | 0.80 | MAPK8 (0.50) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264882 | 0.80 | KDM4E (0.47) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264853 | 0.79 | KDM4E (0.47) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264884 | 0.78 | MAPK8 (0.50) | KMT2AKDM4ESMN1; SMN2ARTSHR | |
| SCHEMBL29264864 | 0.78 | NPSR1 (0.47) | KMT2AKDM4ESMN1; SMN2ARTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |