Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264850 | 0.92 | KDM4E (0.52) | MAPK8PLA2G2AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29264868 | 0.89 | MAPK8 (0.50) | MAPK8KMT2AKDM4ESMN1; SMN2TSHR | |
| SCHEMBL29264863 | 0.88 | SLC6A4 (0.45) | MAPK8KMT2AKDM4EKLK1ALDH1A1 | |
| SCHEMBL29264847 | 0.88 | KDM4E (0.50) | MAPK8KMT2AKDM4ESMN1; SMN2TSHR | |
| SCHEMBL29264864 | 0.87 | NPSR1 (0.47) | MAPK8PLA2G2AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29264853 | 0.86 | KDM4E (0.47) | MAPK8KMT2AKDM4ESMN1; SMN2TSHR | |
| SCHEMBL29264882 | 0.83 | KDM4E (0.47) | MAPK8PLA2G2AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30612331 | 0.82 | KLK1 (0.48) | MAPK8PLA2G2AKMT2ASMN1; SMN2PLA2G1B | |
| SCHEMBL29264871 | 0.81 | NPSR1 (0.47) | MAPK8PLA2G2AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29264856 | 0.78 | KMT2A (0.47) | MAPK8KMT2AKDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |