Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264863 | 0.91 | SLC6A4 (0.45) | KDM4EKMT2ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL29264868 | 0.90 | MAPK8 (0.50) | KDM4ESMN1; SMN2KMT2ATSHRAR | |
| SCHEMBL29264882 | 0.90 | KDM4E (0.47) | KDM4ESMN1; SMN2KMT2ATSHRSLC6A3 | |
| SCHEMBL29264866 | 0.88 | SLC6A3 (0.51) | KDM4ESMN1; SMN2KMT2ASLC6A3SLC6A4 | |
| SCHEMBL29264884 | 0.88 | MAPK8 (0.50) | KDM4ESMN1; SMN2KMT2ATSHRAR | |
| SCHEMBL29264864 | 0.88 | NPSR1 (0.47) | KDM4ESMN1; SMN2KMT2ATSHRSLC6A3 | |
| SCHEMBL29264850 | 0.88 | KDM4E (0.52) | KDM4ESMN1; SMN2KMT2ATSHRAR | |
| SCHEMBL29264859 | 0.88 | NOTUM (0.58) | KDM4ESMN1; SMN2TSHRNOTUMALDH1A1 | |
| SCHEMBL29264841 | 0.87 | TSHR (0.46) | KDM4ESMN1; SMN2KMT2ATSHRAR | |
| SCHEMBL29264858 | 0.87 | SLC6A3 (0.50) | KDM4ESMN1; SMN2KMT2ASLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |