Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525413 | 1.00 | CRBN (0.55) | CRBNDDB1GPR119USP30PDK2 | |
| SCHEMBL22119507 | 0.89 | DDB1 (0.59) | CRBNDDB1GPR119PDK2MAPT | |
| SCHEMBL23173797 | 0.87 | CRBN (0.56) | CRBNDDB1GPR119USP30ALDH1A1 | |
| SCHEMBL30831015 | 0.85 | CRBN (0.54) | CRBNDDB1USP30 | |
| SCHEMBL31201874 | 0.84 | CRBN (0.47) | CRBNDDB1GPR119PDK2MAPT | |
| SCHEMBL27349010 | 0.84 | CRBN (0.47) | CRBNDDB1GPR119PDK2MAPT | |
| SCHEMBL30952388 | 0.84 | DDB1 (0.50) | CRBNDDB1GPR119PDK2MAPT | |
| SCHEMBL30703627 | 0.84 | DDB1 (0.48) | CRBNDDB1GPR119PDK2MAPT | |
| SCHEMBL30257613 | 0.83 | DDB1 (0.52) | CRBNDDB1USP30MAPTALDH1A1 | |
| SCHEMBL25079570 | 0.83 | DDB1 (0.52) | CRBNDDB1USP30MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234726-A | Chimeric compound for androgen receptor protein targeted degradation, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |