Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.54 |
| ▸ | GLS | O94925 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525413 | 0.85 | CRBN (0.55) | CRBNDDB1USP30 | |
| SCHEMBL29265203 | 0.85 | CRBN (0.55) | CRBNDDB1USP30 | |
| SCHEMBL23173797 | 0.83 | CRBN (0.56) | CRBNDDB1USP30 | |
| SCHEMBL31630937 | 0.83 | CRBN (0.68) | CRBNDDB1USP30PARP1CCNK | |
| SCHEMBL25079570 | 0.82 | DDB1 (0.52) | CRBNDDB1USP30 | |
| SCHEMBL30257613 | 0.82 | DDB1 (0.52) | CRBNDDB1USP30 | |
| SCHEMBL25583719 | 0.81 | CRBN (0.66) | CRBNDDB1USP30PARP1 | |
| SCHEMBL30087031 | 0.80 | DDB1 (0.52) | CRBNDDB1USP30 | |
| SCHEMBL22119581 | 0.80 | DDB1 (0.52) | CRBNDDB1USP30 | |
| SCHEMBL23120553 | 0.79 | DDB1 (0.50) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |