Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523721 | 0.92 | OPRM1 (0.43) | OPRM1SPHK1TP53CA1FDPS | |
| SCHEMBL29100513 | 0.86 | OPRM1 (0.39) | OPRM1SPHK1TP53CA1FDPS | |
| SCHEMBL11328501 | 0.85 | FDPS (0.38) | OPRM1SPHK1TP53CA1FDPS | |
| SCHEMBL29265238 | 0.85 | OPRM1 (0.44) | OPRM1SPHK1TP53CA1FDPS | |
| SCHEMBL25217251 | 0.85 | FDPS (0.33) | FDPS | |
| SCHEMBL28272249 | 0.83 | SPHK1 (0.45) | OPRM1SPHK1TP53FDPSLMNA | |
| SCHEMBL12810646 | 0.79 | OPRM1 (0.43) | OPRM1SPHK1TP53CA1FDPS | |
| SCHEMBL6056355 | 0.78 | SPHK1 (0.48) | OPRM1SPHK1TP53FDPSLMNA | |
| SCHEMBL27522551 | 0.78 | FDPS (0.34) | FDPS | |
| SCHEMBL17201413 | 0.77 | SPHK1 (0.47) | OPRM1SPHK1TP53FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176179-A | Novel spiro compounds | 田边三菱制药株式会社 | 2024-06-11 | — | — | CN | disclosed |