Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.58 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.58 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL6544851 | 0.89 | NR4A2 (0.56) | MAPK1EGLN1NR4A2KEAP1ALDH1A1 | |
| Alpha-Ketoglutaric Acid SCHEMBL10389244 | 0.88 | MAPK1 (0.58) | MAPK1SLC13A3EGLN1OR51E2NR4A2 | |
| Oxaloacetate SCHEMBL28495903 | 0.81 | FEN1 (0.52) | MAPK1ALDH1A1GAASMN1; SMN2CYP3A4 | |
| Alpha-Ketoglutaric Acid SCHEMBL9449888 | 0.79 | CYP1A2 (0.52) | MAPK1SLC13A3EGLN1OR51E2NR4A2 | |
| Alpha-Ketoglutaric Acid SCHEMBL27546478 | 0.78 | AKR1B1 (0.68) | MAPK1SLC13A3EGLN1OR51E2NR4A2 | |
| Oxalic Acid SCHEMBL7625758 | 0.77 | ALOX15 (0.62) | MAPK1ALDH1A1GAACYP2C19SMN1; SMN2 | |
| Alpha-Ketoglutaric Acid SCHEMBL29162802 | 0.77 | EGLN1 (0.88) | MAPK1SLC13A3EGLN1OR51E2CYP1A2 | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.76 | EGLN1 (1.00) | MAPK1SLC13A3EGLN1OR51E2LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.76 | EGLN1 (1.00) | MAPK1SLC13A3EGLN1OR51E2LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL17127347 | 0.76 | EGLN1 (1.00) | MAPK1SLC13A3EGLN1OR51E2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118021977-A | Application of prolyl hydroxylase inhibitor in preparation of medicines for preventing and/or treating platelet thrombosis | 南开大学 | 2024-05-14 | — | — | CN | disclosed |