Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265441 | 0.90 | KDM4E (0.32) | SMN1; SMN2MAPTKMT2ALMNAMEN1 | |
| SCHEMBL18355979 | 0.89 | KMT2A (0.35) | MAPK1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL29265442 | 0.89 | MAPK1 (0.36) | MAPK1SMN1; SMN2MAPTKMT2ATP53 | |
| SCHEMBL16863522 | 0.84 | MLYCD (0.36) | RXFP1 | |
| SCHEMBL18355980 | 0.83 | POLB (0.35) | MAPK1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL29265438 | 0.83 | JAK2 (0.31) | JAK2JAK1 | |
| SCHEMBL18354046 | 0.83 | TSHR (0.35) | KMT2AALDH1A1MEN1 | |
| SCHEMBL17482099 | 0.83 | HTT (0.41) | MAPK1SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL18354409 | 0.82 | DHODH (0.33) | SMN1; SMN2MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL18355932 | 0.82 | MLYCD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026883-A | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-05-14 | — | — | CN | disclosed |