SCHEMBL29265663

SCHEMBL29265663

CC(C)(C)NC(=O)O[C@@H]1CCN(c2cccc(Br)n2)C1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 17/20 0.43
HRH3 Q9Y5N1 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23500782 0.77 ACACB (0.48) ACACB
SCHEMBL5873570 0.76 MAP4K4 (0.41) ACACB
SCHEMBL29265664 0.76 SUV39H2 (0.55)
SCHEMBL950967 0.76 SUV39H2 (0.55)
SCHEMBL950966 0.76 SUV39H2 (0.55)
SCHEMBL28856275 0.75 GPR119 (0.55) ACACB
SCHEMBL28930859 0.75 LMNA (0.39) ACACBHRH3
SCHEMBL29182899 0.75 UGT8 (0.38) ACACB
SCHEMBL28930950 0.74 LMNA (0.39) ACACB
SCHEMBL23089345 0.74 ACACB (0.44) ACACBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239953-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2024-06-25 CN disclosed