SCHEMBL2926573

SCHEMBL2926573

c1ccc2nc3c(nc2c1)CCCC3

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
BCHE P06276 5/20 0.53
ACHE P22303 5/20 0.53
ALDH1A1 P00352 3/20 0.53
TSHR P16473 3/20 0.53
HSD17B10 Q99714 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
KDM4E B2RXH2 2/20 0.53
CACNB4 O00305 1/20 0.53
CACNA1A O00555 1/20 0.53
SLC22A2 O15244 1/20 0.53
SLC22A1 O15245 1/20 0.53
ABCC4 O15439 1/20 0.53
CACNA1G O43497 1/20 0.53
CACNG3 O60359 1/20 0.53
CACNA1F O60840 1/20 0.53
CACNA1H O95180 1/20 0.53
APP P05067 1/20 0.53
FABP1 P07148 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14572403 0.94 BCHE (0.53) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL7695584 0.82 NPC1 (0.58) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL25409087 0.79 MAPT (0.48) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL26363970 0.79 MAPT (0.48) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL25409084 0.79 MAPT (0.48) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL6313436 0.77 HTR2C (0.48) ALDH1A1HSD17B10CYP1A2KDM4ECYP3A4
SCHEMBL452908 0.75 NPC1 (0.49) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL9823209 0.74 HTT (0.47) KMT2ABCHEACHEALDH1A1TSHR
SCHEMBL8326392 0.74 ACHE (0.54) BCHEACHEALDH1A1TSHRHSD17B10
SCHEMBL9347454 0.74 KMT2A (0.48) KMT2ABCHEACHEALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110776472-B Preparation method of tetrahydrophenazine derivative 五邑大学 2022-04-22 CN claimed
CN-110776472-A Preparation method of tetrahydrophenazine derivative 五邑大学 2020-02-11 CN claimed
WO-2013005170-A2 INHIBITORS OF AQUAGLYCEROPORINS, METHODS AND USES THEREOF UNIVERSIDADE DE LISBOA (PT) 2013-01-10 WO claimed
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-28 US disclosed
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-05-26 US disclosed
CN-122071471-A Heterocyclic compounds 武田药品工业株式会社 2026-05-22 CN disclosed
EP-3617208-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2026-05-13 EP disclosed
CN-122010945-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
CN-122010946-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
US-20260092033-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2026-04-02 US disclosed
US-12534471-B2 Pyrrolo[1, 2-c]imidazole derivatives as orexin type 2 receptor agonists and methods of use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-01-27 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0237915-A2 Chromogenic phthalides, their preparation and use BAYER AG (DE) 1987-09-23 EP disclosed
EP-0092862-B1 PROCESS FOR THE OXIDATION OF TERTIARY AMINES TO AMINE OXIDES THE PROCTER & GAMBLE COMPANY (US) 1986-03-12 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4565891-A Oxidation of tertiary amines using octacyanomolybdate or iron (III) salts as catalysts THE PROCTER & GAMBLE COMPANY (US) 1986-01-21 US disclosed
EP-0092862-A1 Process for the oxidation of tertiary amines to amine oxides THE PROCTER & GAMBLE COMPANY (US) 1983-11-02 EP disclosed
US-4140686-A BY RECRYSTALLIZATION FROM AN ALKYL ESTER OF AN ALIPHATIC CARBOXYLIC ACID TORAY INDUSTRIES, INC. (JP) 1979-02-20 US disclosed
US-4140686-A BY RECRYSTALLIZATION FROM AN ALKYL ESTER OF AN ALIPHATIC CARBOXYLIC ACID TORAY INDUSTRIES, INC. (JP) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092033-A1 HETEROCYCLIC COMPOUND AND USE THEREOF HCRTR2, HCRTR1, MTNR1B KMT2A 186/4885BCHE 745/4885ACHE 2739/4885
US-12637418-B2 Heterocyclic compounds as antagonist of NMDA GRIN1, GRIN3A, GRIN2A KMT2A 625/4885BCHE 837/4885ACHE 690/4885
US-20260146047-A1 MACROCYCLIC HETEROCYCLE COMPOUNDS AND USE THEREOF HCRTR2, HCRTR1, NPY1R KMT2A 507/4885BCHE 1795/4885ACHE 3754/4885
US-12534471-B2 Pyrrolo[1, 2-c]imidazole derivatives as orexin type 2 receptor agonists and methods of use thereof HCRTR2, HCRTR1, NPY1R KMT2A 1264/4885BCHE 719/4885ACHE 1248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.