SCHEMBL292658

SCHEMBL292658

[c]1c(-c2ccccc2)ccc2cc3ccccc3cc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
HSD17B10 Q99714 4/20 0.34
CYP3A4 P08684 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
CYP1A2 P05177 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2459864 0.86 ESR1 (0.38) ALDH1A1HSD17B10CYP3A4TDP1ALOX15
SCHEMBL291173 0.86 GSTP1 (0.42) ALDH1A1HSD17B10ESR1ESR2HSD17B1
SCHEMBL2152944 0.85 TDP1 (0.44) ALDH1A1HSD17B10CYP3A4TDP1CYP1A2
SCHEMBL79020 0.81 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1MEN1KMT2A
SCHEMBL29093556 0.78 ESR1 (0.46) ALDH1A1HSD17B10ALOX15ESR1ESR2
SCHEMBL3149589 0.78 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP3A4TDP1ESR1
SCHEMBL4718441 0.76 CYP3A4 (0.33) ALDH1A1HSD17B10CYP3A4TDP1ALOX15
SCHEMBL28786162 0.76 CYP2A6 (0.45) ALDH1A1CYP1A2KDM4EMEN1TP53
SCHEMBL10594294 0.76 ESR2 (0.52) ALDH1A1CYP3A4ESR1ESR2HSD17B1
SCHEMBL27802197 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4383988-A1 ORGANIC LIGHT EMITTING DIODE, DEVICE COMPRISING THE SAME AND COMPOUND Novaled GmbH (DE) 2024-06-12 EP claimed
CN-111051303-B Nitrogen-containing cyclic compound and color conversion film comprising same 株式会社LG化学 2023-06-02 CN claimed
CN-115710278-A Fluoranthene oxazepine organic compound and preparation method and application thereof 烟台九目化学股份有限公司 2023-02-24 CN claimed
CN-115677603-A Organic electroluminescent compound and preparation method and application thereof 阜阳欣奕华材料科技有限公司 2023-02-03 CN claimed
CN-114805092-A Compound and organic electroluminescent device 南京高光半导体材料有限公司 2022-07-29 CN claimed
CN-109411631-B Terpyridine derivative and application thereof in organic luminescent material 北京鼎材科技有限公司 2022-03-15 CN claimed
WO-2021136055-A1 NITROGEN-CONTAINING ORGANIC COMPOUND, USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO claimed
CN-111116584-B Nitrogen-containing organic compound, application thereof and organic electroluminescent device using nitrogen-containing organic compound 陕西莱特光电材料股份有限公司 2021-01-22 CN claimed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US claimed
CN-111116584-A Nitrogen-containing organic compound, application thereof and organic electroluminescent device using nitrogen-containing organic compound 陕西莱特光电材料股份有限公司 2020-05-08 CN claimed
EP-0681019-A2 Phenylanthracene derivative and organic EL element TDK Corporation (JP) 1995-11-08 EP claimed
EP-0052510-B2 Microencapsulation of water soluble polypeptides SYNTEX INC (US) 1994-10-19 EP claimed
EP-0293632-B1 DELIVERY SYSTEMS FOR THE CONTROLLED ADMINISTRATION OF LHRH ANALOGS SYNTEX (U.S.A.) INC. (US) 1992-10-07 EP claimed
EP-0166682-B1 PROCESS FOR OBTAINING POSITIVE IMAGES CIBA-GEIGY AG (CH) 1992-01-08 EP claimed
US-4959217-A HYDROGEL, RATE-LIMITING MEMBRANE SYNTEX (U.S.A.) INC. (US) 1990-09-25 US claimed
EP-0293632-A1 Delivery systems for the controlled administration of LHRH analogs SYNTEX (U.S.A.) INC. (US) 1988-12-07 EP claimed
US-4675189-A USING BIODEGRADABLE POLYMER; SUSTAINED RELEASE SYNTEX (U.S.A.) INC. (US) 1987-06-23 US claimed
EP-0052510-B1 MICROENCAPSULATION OF WATER SOLUBLE POLYPEPTIDES SYNTEX (U.S.A.) INC. (US) 1986-08-27 EP claimed
EP-0166682-A2 Process for obtaining positive images CIBA-GEIGY AG (CH) 1986-01-02 EP claimed
EP-0052510-A2 Microencapsulation of water soluble polypeptides SYNTEX (U.S.A.) INC. (US) 1982-05-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 ALDH1A1 470/4885HSD17B10 3244/4885CYP3A4 416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.