Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177833 | 0.85 | MEN1 (0.34) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25804225 | 0.83 | MAPT (0.37) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21177683 | 0.81 | GPX4 (0.37) | HRH3MEN1KMT2AMAPTTP53 | |
| SCHEMBL28475670 | 0.81 | GPX4 (0.37) | HRH3MEN1KMT2AMAPTTP53 | |
| SCHEMBL21184123 | 0.81 | KMT2A (0.38) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL28481475 | 0.80 | HRH3 (0.35) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21184121 | 0.80 | LMNA (0.41) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL29266544 | 0.80 | HRH3 (0.36) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21184095 | 0.78 | MEN1 (0.37) | MEN1NPC1RAB9AKMT2APYGL | |
| SCHEMBL25804226 | 0.78 | MAPT (0.33) | HRH3MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902403-B | Substituted alkynylene compounds as anticancer agents | 奥里吉恩发现科技有限公司 | 2024-05-17 | — | — | CN | disclosed |