Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922240 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EHTTNPSR1AR | |
| SCHEMBL2927557 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTTNPSR1AR | |
| SCHEMBL2921915 | 0.78 | AR (0.44) | ALDH1A1KDM4EHTTNPSR1AR | |
| SCHEMBL2895832 | 0.78 | KMT2A (0.36) | ALDH1A1KDM4EHTTNPSR1KMT2A | |
| SCHEMBL193133 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL25384296 | 0.70 | AOC3 (0.44) | KDM4EHTTPOLBMAPTAOC3 | |
| SCHEMBL10260750 | 0.67 | KDM4E (0.35) | ALDH1A1KDM4EHTTNPSR1KMT2A | |
| SCHEMBL10960191 | 0.65 | KDM4E (0.37) | ALDH1A1KDM4EHTTNPSR1AR | |
| SCHEMBL7959800 | 0.64 | GAA (0.40) | ALDH1A1KDM4EHTTNPSR1KMT2A | |
| SCHEMBL30937756 | 0.64 | GAA (0.40) | ALDH1A1KDM4EHTTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940849-B1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-1915344-B1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080207447-A1 | Cyanopyridine Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1940849-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1915344-A1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007093530-A1 | THIOAMIDE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007014913-A1 | CYANOPYRIDINE PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | IPO5, PIR, ACHE | ALDH1A1 2385/4885KDM4E 2453/4885HTT 503/4885 |
| US-20080207447-A1 | Cyanopyridine Pesticides | CBR3, CBR1, CHRM1 | ALDH1A1 3463/4885KDM4E 3267/4885HTT 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.