Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928219 | 0.88 | KMT2A (0.42) | KMT2AIDO1MDM2PTPN1PAX8 | |
| SCHEMBL31714189 | 0.82 | KMT2A (0.45) | KMT2AIDO1MDM2MALT1TLR2 | |
| SCHEMBL2928823 | 0.81 | KMT2A (0.38) | KMT2AMDM2MALT1TLR2TLR1 | |
| SCHEMBL2928612 | 0.80 | KDM4E (0.39) | KMT2AIDO1MDM2MALT1CTSL | |
| SCHEMBL2924241 | 0.77 | KMT2A (0.41) | KMT2AMDM2CTSLPAX8TDP1 | |
| SCHEMBL5973227 | 0.77 | KMT2A (0.50) | KMT2AIDO1MDM2MALT1TLR2 | |
| SCHEMBL25355524 | 0.77 | KMT2A (0.41) | KMT2AMDM2TDP1 | |
| SCHEMBL31369807 | 0.77 | KMT2A (0.41) | KMT2AMDM2TDP1 | |
| SCHEMBL25355520 | 0.77 | KMT2A (0.41) | KMT2AMDM2TDP1 | |
| SCHEMBL30685999 | 0.76 | KMT2A (0.48) | KMT2AMDM2MALT1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675824-B1 | SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS | WURSTER SIEGFRIED (FI) | 2010-09-29 | — | — | EP | disclosed |
| US-7741362-B2 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | SIEGFRIED WURSTER (FI) | 2010-06-22 | — | — | US | disclosed |
| US-20100004339-A1 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists | OY JUVANTIA PHARMA LTD. (FI) | 2010-01-07 | — | — | US | disclosed |
| EP-1678196-B1 | SULFONYLAMINO-PEPTIDOMIMETICS ACTIVE ON THE SOMATOSTATIN RECEPTOR SUBTYPES 4 (SSTR4) AND 1 (SSTR1) | WURSTER SIEGFRIED (FI) | 2008-08-13 | — | — | EP | disclosed |
| US-20070129422-A1 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | OY JUVANTIA PHARMA LTD (FI) | 2007-06-07 | — | — | US | disclosed |
| US-20070129313-A1 | Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1) | SIEGFRIED WURSTER (FI) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129422-A1 | Somatostatin receptor 1 and/or 4 selective agonists and antagonists | SSTR4, SSTR1, SSTR3 | KMT2A 2112/4885IDO1 1949/4885MDM2 3756/4885 |
| US-20070129313-A1 | Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1) | SSTR4, SSTR1, SSTR3 | KMT2A 3881/4885IDO1 1614/4885MDM2 3395/4885 |
| US-20100004339-A1 | Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists | SSTR4, SSTR1, SSTR3 | KMT2A 2112/4885IDO1 1949/4885MDM2 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.