Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | PRNP | P04156 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | NR0B1 | P51843 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brefeldin A SCHEMBL4967925 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL30460472 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL17167480 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL30460466 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL12648486 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL29268 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL13073124 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL4967944 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL4345242 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP | |
| Brefeldin A SCHEMBL8264765 | 1.00 | NPC1 (1.00) | NPC1RAB9ALMNASMN1; SMN2PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026086871-A1 | ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING | Centre for Translational Stem Cell Biology Limited (CN) | 2026-04-30 | — | — | WO | claimed |
| US-12577219-B2 | Macrolide brefeldin a ester derivatives and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2026-03-17 | — | — | US | claimed |
| US-12522590-B2 | Brefeldin a derivatives, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2026-01-13 | — | — | US | claimed |
| US-20250354152-A1 | PHARMACEUTICAL COMPOUND FOR PREVENTION OR TREATMENT OF LIVER FIBROSIS | MEDIZINISCHE HOCHSCULE HANNOVER (DE) | 2025-11-20 | — | — | US | claimed |
| EP-4615576-A1 | CELLS BEING HIGHLY ENRICHED IN SASP FACTORS, AND COMPOSITION COMPRISING SAID CELLS | Evomedis GmbH (AT) | 2025-09-17 | — | — | EP | claimed |
| CN-120137050-A | Chimeric cytokine receptor for activating lymphocytes by using soluble immunosuppressive molecules and application of chimeric cytokine receptor in tumor treatment | 中国人民解放军海军军医大学 | 2025-06-13 | — | — | CN | claimed |
| US-20250134926-A1 | COMPOSITION FOR ANTI-CANCER TREATMENT COMPRISING IMMUNOGENIC TUMOR-DERIVED EXTRACELLULAR VESICLES USING AN ENDOPLASMIC RETICULUM STRESS INDUCER AND METHOD FOR PRODUCING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2025-05-01 | — | — | US | claimed |
| WO-2025082418-A1 | METHOD FOR IDENTIFYING TARGET AND USE THEREOF | 苏州沙砾生物科技有限公司 | 2025-04-24 | — | — | WO | claimed |
| EP-4536826-A1 | PHARMACEUTICAL COMPOUND FOR PREVENTION OR TREATMENT OF LIVER FIBROSIS | Medizinische Hochschule Hannover (DE) | 2025-04-16 | — | — | EP | claimed |
| CN-116218690-B | Curvularia robusta producing cloth Lei Feide bacteria A and fermentation method thereof | 浙江珲达生物科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| EP-0683225-A1 | Process for production of inositol and microorganism used therefor | TORAY INDUSTRIES, INC. (JP) | 1995-11-22 | — | — | EP | claimed |
| EP-0663958-A1 | INHIBITION OF CYST FORMATION BY CYTOSKELETAL SPECIFIC DRUGS | Woo, David D.L. (US) | 1995-07-26 | — | — | EP | claimed |
| EP-0617619-A1 | USE OF APP MODULATORS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF AMYLOIDOSIS | THE ROCKEFELLER UNIVERSITY (US) | 1994-10-05 | — | — | EP | claimed |
| WO-1994021271-A1 | METHODS AND COMPOSITIONS FOR INDUCING PHASE SEPARATION OF EPITHELIAL LIPID BILAYERS | CELLEGY PHARMACEUTICALS, INC. (US) | 1994-09-29 | — | — | WO | claimed |
| WO-1994008041-A1 | INHIBITION OF CYST FORMATION BY CYTOSKELETAL SPECIFIC DRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-04-14 | — | — | WO | claimed |
| US-5254342-A | Compositions and methods for enhanced transepithelial and transendothelial transport or active agents | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1993-10-19 | — | — | US | claimed |
| US-5242932-A | TREATMENT OF AMYLOIDOSIS ASSOCIATED WITH ALZHEIMER DISEASE | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-07 | — | — | US | claimed |
| WO-1993011762-A1 | USE OF APP MODULATORS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF AMYLOIDOSIS | THE ROCKEFELLER UNIVERSITY (US) | 1993-06-24 | — | — | WO | claimed |
| US-5112607-A | Potentiation of immunotoxin action by Brefeldin A | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1992-05-12 | — | — | US | claimed |
| US-4608078-A | Brefeldin A derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1986-08-26 | — | — | US | claimed |