SCHEMBL2926729

SCHEMBL2926729

[C]#Cc1ccccc1N(c1ccccc1)c1ccc(C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.37
APP P05067 1/20 0.35
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
C5AR1 P21730 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2923196 0.89 ALDH1A1 (0.37) CYP2C19ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL8105552 0.81 CYP2C19 (0.47) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL29268252 0.81 CYP2C19 (0.47) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL2146885 0.81 CYP2C19 (0.47) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL18051490 0.79 TSHR (0.45) CYP2C19ALDH1A1HPGDKDM4ECYP1A2
SCHEMBL7147096 0.77 TSHR (0.48) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL10053558 0.76 CYP2C19 (0.42) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL17358865 0.76 CYP2C19 (0.42) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL1900258 0.76 CYP2C19 (0.42) CYP2C19APPALDH1A1L3MBTL1HPGD
SCHEMBL13990423 0.74 ALDH1A1 (0.56) CYP2C19APPALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1342769-B1 Organic EL Device TDK CORP (JP) 2010-01-27 EP disclosed
EP-1992672-A1 Organic electroluminescent device TDK Corporation (JP) 2008-11-19 EP disclosed
US-20070202354-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO.,LTD (JP) 2007-08-30 US disclosed
EP-1737277-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2006-12-27 EP disclosed
EP-0857007-B1 ORGANIC ELECTROLUMINESCENT DEVICE TDK CORP (JP) 2004-07-21 EP disclosed
US-6713192-B2 WHERE THE ORGANIC LIGHT EMITTING MEDIUM COMPRISES AN ELECTRON TRANSPORT COMPOUND AND SPECIFIED ANTHRACENE DERIVATIVE(S); HEAT RESISTANCE, EFFICIENCY, DURABILITY IDEMITSU KOSAN CO., LTD. (JP) 2004-03-30 US disclosed
EP-1342769-A1 Organic EL Device TDK Corporation (JP) 2003-09-10 EP disclosed
US-6603140-B2 Organic EL device TDK CORPORATION (JP) 2003-08-05 US disclosed
US-20020048688-A1 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2002-04-25 US disclosed
US-20020038867-A1 Organic EL device TDK CORPORATION (JP) 2002-04-04 US disclosed
EP-1191822-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2002-03-27 EP disclosed
US-6285039-B1 HIGH LUMINANCEL CONTINUOUS LIGHT EMISSION AND RELIABILITY; MULTI-COLOR EMISSION MAY BE POSSIBLE TDK CORPORATION (JP) 2001-09-04 US disclosed
US-6203933-B1 ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND TDK CORPORATION (JP) 2001-03-20 US disclosed
EP-0857007-A1 ORGANIC ELECTROLUMINESCENT DEVICE TDK Corporation (JP) 1998-08-05 EP disclosed