SCHEMBL8105552

SCHEMBL8105552

Cc1ccc(N(c2ccc(C)cc2)c2ccccc2N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.47
TSHR P16473 2/20 0.46
ACHE P22303 2/20 0.46
LMNA P02545 1/20 0.46
ALOX12 P18054 1/20 0.46
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
APP P05067 1/20 0.42
C5AR1 P21730 1/20 0.39
HPGD P15428 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29268252 1.00 CYP2C19 (0.47) CYP2C19TSHRACHELMNAALOX12
SCHEMBL2146885 1.00 CYP2C19 (0.47) CYP2C19TSHRACHELMNAALOX12
SCHEMBL7147096 0.95 TSHR (0.48) CYP2C19TSHRACHELMNAALOX12
SCHEMBL7013209 0.90 ALDH1A1 (0.63) CYP2C19TSHRACHELMNAALOX12
SCHEMBL14466518 0.90 ALDH1A1 (0.41) CYP2C19TSHRACHELMNAALOX12
SCHEMBL7009406 0.90 ALDH1A1 (0.63) CYP2C19TSHRACHELMNAALOX12
SCHEMBL10053558 0.89 CYP2C19 (0.42) CYP2C19TSHRACHELMNAALOX12
SCHEMBL1900258 0.89 CYP2C19 (0.42) CYP2C19TSHRACHELMNAALOX12
SCHEMBL17358865 0.89 CYP2C19 (0.42) CYP2C19TSHRACHELMNAALOX12
SCHEMBL43023 0.87 ALDH1A1 (0.56) CYP2C19TSHRACHELMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045276-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-18 EP claimed
EP-1045276-A1 ELECTROCHROMIC ELEMENT Nippon Mitsubishi Oil Corporation (JP) 2000-10-18 EP disclosed