SCHEMBL2926734

SCHEMBL2926734

CCCCCCCC(N)[SiH](OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 2/20 0.41
TP53 P04637 2/20 0.39
CYP2D6 P10635 2/20 0.38
LMNA P02545 2/20 0.38
LAP3 P28838 2/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38
UBE2N P61088 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2926600 1.00 OPRM1 (0.48) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL2927189 0.98 OPRM1 (0.50) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL2827730 0.91 OPRM1 (0.41) OPRM1SPHK1TP53
SCHEMBL142952 0.82 OPRM1 (0.33) OPRM1
SCHEMBL3639487 0.82 OPRM1 (0.33) OPRM1
SCHEMBL2925695 0.81 OPRM1 (0.44) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL2925158 0.81 OPRM1 (0.44) OPRM1SPHK1TP53CYP2D6LMNA
Bromide SCHEMBL8028722 0.80 OPRM1 (0.32) OPRM1
SCHEMBL2927845 0.78 OPRM1 (0.46) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL28343743 0.78 OPRM1 (0.41) OPRM1SPHK1TP53CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772421-B2 Polymers with improved strength comprising mixed oxyalkyl units HENKEL AG & CO. KGAA (DE) 2014-07-08 US disclosed
EP-1668090-B1 COHESION-REDUCED BINDER PRODUCTION AND USE THEREOF IN DETACHABLE ASSEMBLY ADHESIVES HENKEL AG & CO KGAA (DE) 2010-09-08 EP disclosed
EP-1678254-B1 POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS HENKEL KGAA (DE) 2007-05-09 EP disclosed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-20060205859-A1 Polyurethane compositions with NCO and silyl reactivity HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-09-14 US disclosed
US-20060194930-A1 Polymers with improved strength comprising mixed oxyalkyl units HENKEL AG & CO. KGAA (DE) 2006-08-31 US disclosed
US-20060178470-A1 Cohesion-reduced binder production and use thereof in detachable assembly adhesives HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-08-10 US disclosed
EP-1685175-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY Henkel Kommanditgesellschaft auf Aktien (DE) 2006-08-02 EP disclosed
EP-1678254-A1 POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS Henkel Kommanditgesellschaft auf Aktien (DE) 2006-07-12 EP disclosed
EP-1668090-A1 COHESION-REDUCED BINDER PRODUCTION AND USE THEREOF IN DETACHABLE ASSEMBLY ADHESIVES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-06-14 EP disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
WO-2005049684-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-02 WO disclosed
WO-2005047394-A1 POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-05-26 WO disclosed
WO-2005044888-A1 STEAM-BLOCKING POLYURETHANE AND ADHESIVE MOULDED BODY PRODUCED THEREFROM HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-05-19 WO disclosed
WO-2005042610-A2 STORAGE-STABLE POLYURETHANE COMPRISING SILYL GROUPS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-05-12 WO disclosed
WO-2005033241-A1 COHESION-REDUCED BINDER PRODUCTION AND USE THEREOF IN DETACHABLE ASSEMBLY ADHESIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-04-14 WO disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed