Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639487 | 0.98 | OPRM1 (0.33) | OPRM1 | |
| SCHEMBL142952 | 0.98 | OPRM1 (0.33) | OPRM1 | |
| SCHEMBL2827730 | 0.84 | OPRM1 (0.41) | OPRM1 | |
| SCHEMBL2927189 | 0.82 | OPRM1 (0.50) | OPRM1 | |
| SCHEMBL1069119 | 0.81 | — | — | |
| SCHEMBL2926734 | 0.80 | OPRM1 (0.48) | OPRM1 | |
| SCHEMBL2926600 | 0.80 | OPRM1 (0.48) | OPRM1 | |
| SCHEMBL22289365 | 0.77 | ADRB2 (0.37) | OPRM1 | |
| SCHEMBL472156 | 0.77 | — | — | |
| SCHEMBL142524 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983317-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE AS FILLERS IN POLYMER MASTERBATCHES | Bayer Inc. (CA) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998053004-A1 | PROCESS FOR HYDROPHOBICIZING PARTICLES, AND THEIR USE AS FILLERS IN POLYMER MASTERBATCHES | BAYER INC. (CA) | 1998-11-26 | — | — | WO | disclosed |