Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267445 | 0.80 | GRM5 (0.42) | KDM4E | |
| SCHEMBL29267456 | 0.77 | CYP2A6 (0.41) | PIM3KDM4E | |
| SCHEMBL9591539 | 0.77 | MAOB (0.46) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL9360788 | 0.77 | PARP1 (0.49) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL29267433 | 0.77 | PARP1 (0.41) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL4466003 | 0.75 | SORT1 (0.46) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL25229015 | 0.74 | TDP1 (0.50) | PARP1 | |
| SCHEMBL28783999 | 0.74 | PARP1 (0.39) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL21143432 | 0.73 | EGFR (0.44) | PARP1GSK3AGSK3BCLK4DYRK3 | |
| SCHEMBL29267463 | 0.73 | ALDH1A1 (0.49) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |