SCHEMBL29268293

SCHEMBL29268293

O=C1OC(=O)c2cc(C#CC3CCCCC3)ccc21

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 8/20 0.43
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 2/20 0.43
NPC1 O15118 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
KCNH2 Q12809 1/20 0.40
CYP1A2 P05177 1/20 0.39
PRKD1 Q15139 1/20 0.38
HAO1 Q9UJM8 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
CREBBP Q92793 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2640689 0.78 GRM5 (0.53) GRM5
SCHEMBL9611211 0.76 GRM5 (0.56) GRM5
SCHEMBL12314488 0.75 ALOX15 (0.46) GRM5
SCHEMBL2126775 0.72 GRM5 (0.43) GRM5CYP1A2
SCHEMBL72823 0.72 GRM5 (0.66) GRM5MAPT
SCHEMBL2809219 0.72 CREBBP (0.45) GRM5FFAR1FFAR4KCNH2CYP1A2
SCHEMBL12314490 0.70 GRM5 (0.42) GRM5
SCHEMBL23374559 0.69 HDAC4 (0.45) MAPT
SCHEMBL4577919 0.69 GRM5 (0.49) GRM5KCNH2CYP1A2
SCHEMBL24080674 0.69 GRM5 (0.45) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221935-A Polyamide acid slurry with low water absorption rate and polyimide film prepared from polyamide acid slurry 武汉柔显科技股份有限公司 2024-06-21 CN claimed
CN-118221935-A Polyamide acid slurry with low water absorption rate and polyimide film prepared from polyamide acid slurry 武汉柔显科技股份有限公司 2024-06-21 CN disclosed