Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 7/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29268952 | 1.00 | DGAT2 (0.39) | DGAT2HDAC1HDAC6PIM1SLC5A1 | |
| SCHEMBL30474041 | 1.00 | DGAT2 (0.39) | DGAT2HDAC1HDAC6PIM1SLC5A1 | |
| SCHEMBL30474032 | 0.91 | HDAC1 (0.37) | HDAC1HDAC6PIM1SLC5A1 | |
| SCHEMBL25213305 | 0.91 | DGAT2 (0.38) | DGAT2HDAC1HDAC6PIM1MAP3K7 | |
| SCHEMBL29268943 | 0.91 | DGAT2 (0.38) | DGAT2HDAC1HDAC6PIM1MAP3K7 | |
| SCHEMBL29268944 | 0.91 | DGAT2 (0.38) | DGAT2HDAC1HDAC6PIM1MAP3K7 | |
| SCHEMBL30474059 | 0.91 | HDAC1 (0.44) | HDAC1HDAC6PIM1RORC | |
| SCHEMBL24073258 | 0.91 | HDAC1 (0.44) | HDAC1HDAC6PIM1RORC | |
| SCHEMBL30474019 | 0.90 | FAAH (0.34) | HDAC1HDAC6RORC | |
| SCHEMBL25675712 | 0.90 | FAAH (0.34) | HDAC1HDAC6RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302422-A | Substituted N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |