SCHEMBL2926906

SCHEMBL2926906

CCCCC(N)[SiH](OC)OC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.37
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
DNM1 Q05193 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
SLC15A1 P46059 1/20 0.31
CYP3A4 P08684 1/20 0.31
TP53 P04637 1/20 0.30
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2927845 0.93 OPRM1 (0.46) OPRM1SLC1A2SLC1A1SPHK1CYP3A4
SCHEMBL2925158 0.91 OPRM1 (0.44) OPRM1SPHK1CYP3A4TP53LAP3
SCHEMBL2925695 0.91 OPRM1 (0.44) OPRM1SPHK1CYP3A4TP53LAP3
SCHEMBL142524 0.85
Methyl Alcohol SCHEMBL8086882 0.81 METAP1 (0.31)
SCHEMBL7099528 0.79 GSR (0.35) DNM1CA1CA2
SCHEMBL2827730 0.79 OPRM1 (0.41) OPRM1ALDH1A1TDP1DNM1CA1
SCHEMBL8101542 0.77 DNM1 (0.35) ALDH1A1DNM1CA1CA2
SCHEMBL5157614 0.77 DNM1 (0.35) ALDH1A1DNM1CA1CA2
SCHEMBL8470115 0.75 DNM1 (0.42) ALDH1A1TDP1DNM1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189910-B1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES CROMPTON CORP (US) 2003-08-27 EP claimed
EP-1189910-A1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES Crompton Corporation (US) 2002-03-27 EP claimed
US-6204403-B1 REACTING AN AMINOAALKYLALKOXYSILANE WITH ACRYLIC ESTER CROMPTON CORPORATION 2001-03-20 US claimed
WO-2000075148-A1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES CROMPTON CORPORATION (US) 2000-12-14 WO claimed
CN-113748134-A Conjugated diene copolymer and method for producing conjugated diene copolymer 瑞住合成橡胶株式会社 2021-12-03 CN disclosed
US-8772421-B2 Polymers with improved strength comprising mixed oxyalkyl units HENKEL AG & CO. KGAA (DE) 2014-07-08 US disclosed
US-7811480-B2 Photochromic optical article TRANSITIONS OPTICAL, INC. (US) 2010-10-12 US disclosed
EP-1668090-B1 COHESION-REDUCED BINDER PRODUCTION AND USE THEREOF IN DETACHABLE ASSEMBLY ADHESIVES HENKEL AG & CO KGAA (DE) 2010-09-08 EP disclosed
EP-1720955-B1 PHOTOCHROMIC OPTICAL ARTICLE TRANSITIONS OPTICAL INC (US) 2010-03-24 EP disclosed
US-7410691-B2 Photochromic optical article PPG INDUSTRIES OHIO, INC. (US) 2008-08-12 US disclosed
US-7261843-B2 A transparent polymeric (polycarbonate) substrate (lens) having a transparent photochromic organic polymeric (polyester) coating appended to the surface; abrasion resistant, antireflective coating affixed to a maleimide derivative-containing film TRANSITIONS OPTICAL, INC. (US) 2007-08-28 US disclosed
EP-1678254-B1 POLYMERS WITH IMPROVED STRENGTH COMPRISING MIXED OXYALKYL UNITS HENKEL KGAA (DE) 2007-05-09 EP disclosed
US-20040207809-A1 Photochromic optical article TRANSITIONS OPTICAL LIMITED (IE) 2004-10-21 US disclosed
EP-1189910-B1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES CROMPTON CORP (US) 2003-08-27 EP disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002050020-A1 METHOD FOR PRODUCING ISOCYANATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-27 WO disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed
EP-1189910-A1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES Crompton Corporation (US) 2002-03-27 EP disclosed
US-6204403-B1 REACTING AN AMINOAALKYLALKOXYSILANE WITH ACRYLIC ESTER CROMPTON CORPORATION 2001-03-20 US disclosed
WO-2000075148-A1 PROCESS FOR MANUFACTURING ACRYLAMIDOALKYLALKOXYSILANES CROMPTON CORPORATION (US) 2000-12-14 WO disclosed