Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.67 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | RRM1 | P23921 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80555 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL3789783 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL3055110 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19468503 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL2185171 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19468457 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL76613 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL944633 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19468513 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL1820932 | 1.00 | EPHX1 (0.67) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118368985-A | Fungicidal compositions | 先正达农作物保护股份公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118019451-A | Fungicidal compositions comprising fludioxonil | 先正达农作物保护股份公司 | 2024-05-10 | — | — | CN | claimed |
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | claimed |
| US-20230110354-A1 | THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2023-04-13 | — | — | US | claimed |
| US-11208361-B2 | Technology to coat fertilizer and improve fertilizer efficiency and their associated methods | MCKNIGHT GARY DAVID (US) | 2021-12-28 | — | — | US | claimed |
| WO-2021252897-A2 | THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-12-16 | — | — | WO | claimed |
| EP-3836971-A1 | CONJUGATES AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2021-06-23 | — | — | EP | claimed |
| US-20210162057-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-06-03 | — | — | US | claimed |
| WO-2020037009-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-02-20 | — | — | WO | claimed |
| CN-110129397-B | Preparation method of oyster peptide | 烟台源力德海洋生物有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-102713033-A | Spandex with high uniformity | INVISTA TECH SARL | 2012-10-03 | — | — | CN | claimed |
| CN-102695708-A | N1-pyrazolospiroketone acetyl-coA carboxylase inhibitors | PFIZER | 2012-09-26 | — | — | CN | claimed |
| US-8263606-B2 | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2012-09-11 | — | — | US | claimed |
| EP-2350090-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2011-08-03 | — | — | EP | claimed |
| CN-101333176-B | Method for preparing substituent urea and co-producing hydrochloride of corresponding amines | UNIV ZHEJIANG TECHNOLOGY | 2011-02-02 | — | — | CN | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| CN-101333176-A | Method for preparing substituent urea and co-producing hydrochloride of corresponding amines | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-12-31 | — | — | CN | claimed |
| CN-101250162-A | Preparation method of agricultural herbicide | YANCHENG LVYE CHEMICAL INDUSTR (CN) | 2008-08-27 | — | — | CN | claimed |
| US-3940370-A | Method of making polyureas | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-02-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210162057-A1 | CONJUGATES AND METHODS OF USING THE SAME | CD47, CD44, CD74 | EPHX1 1102/4885CASP2 1337/4885ZDHHC20 1692/4885 |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | EPHX1 2007/4885CASP2 962/4885ZDHHC20 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.