Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KAT7 | O95251 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269794 | 0.94 | GPR119 (0.51) | GPR119CHEK2 | |
| SCHEMBL31270108 | 0.90 | CHEK2 (0.53) | GPR119CHEK2CYP2C9BACE1CTSD | |
| SCHEMBL31270200 | 0.90 | GPR119 (0.45) | GPR119CHEK2 | |
| SCHEMBL29269366 | 0.90 | GPR119 (0.53) | GPR119CHEK2CYP2C9BACE1CTSD | |
| SCHEMBL31270437 | 0.89 | GPR119 (0.46) | GPR119CHEK2CYP2C9BACE1CTSD | |
| SCHEMBL31270241 | 0.89 | GPR119 (0.43) | GPR119CHEK2CYP2C9BACE1CTSD | |
| SCHEMBL30283409 | 0.88 | ALDH1A1 (0.40) | GPR119CHEK2 | |
| SCHEMBL29269380 | 0.88 | ALDH1A1 (0.40) | GPR119CHEK2 | |
| SCHEMBL29269495 | 0.87 | GPR119 (0.45) | GPR119CHEK2CYP2C9KAT7KAT8 | |
| SCHEMBL31270183 | 0.86 | SCN9A (0.43) | CHEK2CYP2C9BACE1CTSDKAT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251383-A | Macrocyclic compounds as proteasome beta subunit type 5 inhibitors | 利德探索中心有限公司 | 2024-06-25 | — | — | CN | disclosed |