Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | KAT7 | O95251 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269478 | 1.00 | HTR6 (0.45) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL30283224 | 1.00 | HTR6 (0.45) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269496 | 0.92 | HTR6 (0.44) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269498 | 0.92 | HTR6 (0.44) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL30283249 | 0.89 | HTR6 (0.44) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269459 | 0.89 | HTR6 (0.44) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269458 | 0.89 | HTR6 (0.44) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269372 | 0.89 | HTR6 (0.46) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269374 | 0.89 | HTR6 (0.46) | HTR6BCHEUSP30ACKR3KAT7 | |
| SCHEMBL29269379 | 0.88 | HTR6 (0.45) | HTR6BCHEUSP30ACKR3YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251383-A | Macrocyclic compounds as proteasome beta subunit type 5 inhibitors | 利德探索中心有限公司 | 2024-06-25 | — | — | CN | disclosed |