Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26961874 | 0.85 | SRC (0.34) | USP30PDK2USP2ALOX15HSD17B10 | |
| SCHEMBL29270774 | 0.82 | KDM4E (0.32) | TP53 | |
| SCHEMBL29270819 | 0.80 | NOTUM (0.37) | TP53 | |
| SCHEMBL29270852 | 0.77 | PTGDR2 (0.37) | TP53 | |
| SCHEMBL26962164 | 0.75 | PDK2 (0.33) | USP30PDK2USP2ALOX15HSD17B10 | |
| SCHEMBL29270690 | 0.74 | ALDH1A1 (0.41) | TP53 | |
| SCHEMBL26961463 | 0.74 | USP30 (0.35) | USP30 | |
| SCHEMBL29270781 | 0.74 | TP53 (0.37) | TP53 | |
| SCHEMBL29270847 | 0.73 | TP53 (0.47) | TP53 | |
| SCHEMBL29270734 | 0.73 | TP53 (0.31) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |