Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270822 | 0.85 | PLAT (0.30) | — | |
| SCHEMBL29270724 | 0.81 | SSTR4 (0.36) | — | |
| SCHEMBL29270739 | 0.78 | — | — | |
| SCHEMBL26962347 | 0.77 | GAA (0.37) | DGAT1 | |
| SCHEMBL29797169 | 0.77 | GAA (0.37) | DGAT1 | |
| SCHEMBL29270742 | 0.76 | HDAC1 (0.41) | — | |
| SCHEMBL29270801 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL29270754 | 0.73 | AKR1B1 (0.32) | — | |
| SCHEMBL29270794 | 0.73 | HDAC1 (0.39) | — | |
| SCHEMBL29270708 | 0.72 | TP53 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |