Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965925 | 0.93 | TRPM8 (0.60) | TRPM8CHRM3KCNH2 | |
| SCHEMBL30965951 | 0.93 | TRPM8 (0.60) | TRPM8CHRM3KCNH2 | |
| SCHEMBL29271787 | 0.93 | TRPM8 (0.60) | TRPM8CHRM3KCNH2 | |
| SCHEMBL30059415 | 0.93 | TRPM8 (0.60) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22784356 | 0.93 | TRPM8 (0.60) | TRPM8CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL30059449 | 0.92 | TRPM8 (0.59) | TRPM8CHRM3KCNH2 | |
| Trifluoroacetic Acid SCHEMBL22776196 | 0.91 | TRPM8 (0.62) | TRPM8CHRM3KCNH2ESR1ESR2 | |
| SCHEMBL29271843 | 0.86 | TRPM8 (0.53) | TRPM8CHRM3KCNH2 | |
| SCHEMBL25604564 | 0.85 | HHAT (0.57) | TRPM8CHRM3KCNH2ESR1ESR2 | |
| SCHEMBL3061888 | 0.84 | TRPM8 (0.70) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950477-B | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2024-07-05 | — | — | CN | disclosed |