SCHEMBL29272020

SCHEMBL29272020

CN1[CH]N(C(C)(C)C)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
PAX8 Q06710 1/20 0.30
MCL1 Q07820 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29271980 0.85 MEN1 (0.32) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL3308632 0.77 MAOA (0.42) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL25802851 0.75 TLR9 (0.35) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL29011569 0.68 KDM4E (0.35) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL22505286 0.66 MAOA (0.42) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL30542152 0.64 P2RX4 (0.36) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL15262827 0.64 GSK3A (0.35) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL29271962 0.64 MAOA (0.32) MAOAALDH1A1LMNAGAAPAX8
SCHEMBL29011576 0.62 KDM4E (0.40) MAOAALDH1A1LMNA
SCHEMBL24703462 0.62 MAOA (0.44) MAOAALDH1A1LMNAGAAPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290346-A Method for producing amide compound, and amide compound 广荣化学株式会社 2024-07-05 CN disclosed
CN-112703184-B Method for producing amide compound, and amide compound 广荣化学株式会社 2024-06-11 CN disclosed