SCHEMBL3308632

SCHEMBL3308632

CN1[CH]N(C)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.42
GAA P10253 3/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
PAX8 Q06710 1/20 0.39
MCL1 Q07820 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TTR P02766 1/20 0.37
CES1 P23141 1/20 0.37
GPR3 P46089 2/20 0.35
ADRA2C P18825 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
TLR9 Q9NR96 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22505286 0.80 MAOA (0.42) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL15262827 0.77 GSK3A (0.35) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL29272020 0.77 MAOA (0.32) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL29011569 0.77 KDM4E (0.35) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL29271962 0.77 MAOA (0.32) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL29011576 0.75 KDM4E (0.40) MAOAALDH1A1LMNACES1ADRA2C
SCHEMBL13636983 0.72
SCHEMBL29390564 0.72 MAOA (0.60) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL4571020 0.72 MAOA (0.60) MAOAGAAALDH1A1LMNAPAX8
SCHEMBL482716 0.72 MAOA (0.60) MAOAGAAALDH1A1LMNAPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101346372-B Aryl-isoxazol-4-yl-oxadiazole derivatives HOFFMANN LA ROCHE 2011-09-28 CN claimed
CN-118290346-A Method for producing amide compound, and amide compound 广荣化学株式会社 2024-07-05 CN disclosed
CN-112703184-B Method for producing amide compound, and amide compound 广荣化学株式会社 2024-06-11 CN disclosed
CN-109563050-B Amide salt compound, catalyst for polyurethane production and method for producing polyurethane resin 广荣化学株式会社 2023-06-02 CN disclosed
US-20130087682-A1 PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE, AND METHOD FOR DRIVING PHOTOELECTRIC CONVERSION DEVICE FUJIFILM CORPORATION (JP) 2013-04-11 US disclosed
US-8378101-B2 Organic semiconductor, photoelectric conversion device, imaging device and novel compounds FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8278650-B2 Organic semiconductor, photoelectric conversion element and image device FUJIFILM CORPORATION (JP) 2012-10-02 US disclosed
CN-101346372-B Aryl-isoxazol-4-yl-oxadiazole derivatives HOFFMANN LA ROCHE 2011-09-28 CN disclosed
US-20100102303-A1 ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE AND NOVEL COMPOUNDS FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-20090283758-A1 ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION ELEMENT AND IMAGE DEVICE FUJIFILM CORPORATION (JP) 2009-11-19 US disclosed
EP-0138200-A2 Silver halide photographic material and method for forming high contrast negative image using the same FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
EP-0047472-B1 METHOD FOR IMMUNOCHEMICAL MEASUREMENT OF TRACE COMPONENTS FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4447522-A INCLUDING A HYDRAZIDE AND A MERCAPTO AMINE IN THE SILVER HALIDE EMULSION LAYER; LITHOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4429036-A DEVELOPMENT WITH ALKALINE AQUEOUS ACTIVATOR SOLUTION FUJI PHOTO FILM CO., LTD. (JP) 1984-01-31 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
US-4405711-A Analysis element for immunochemical measurement of trace components and method for immunochemical measurement using the same FUJI PHOTO FILM CO., LTD. (JP) 1983-09-20 US disclosed
US-4404289-A REACTING A SPECTRAL SENSITIZER WITH AN ANTIBODY OR ANTIGEN, USE OF HYDRAZIDE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1983-09-13 US disclosed
US-4332878-A USING A HYDROQUINONE DERIVATIVE IN THE SILVER HALIDE EMULSION LAYER AND DEVELOPING IN THE PRESENCE OF A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-01 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047472-A1 Method for immunochemical measurement of trace components FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100102303-A1 ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE AND NOVEL COMPOUNDS H1-3, H1-4, OR10J3 MAOA 2334/4885GAA 4670/4885ALDH1A1 2374/4885
US-20090283758-A1 ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION ELEMENT AND IMAGE DEVICE H1-0, CCNE1, H1-4 MAOA 3010/4885GAA 4655/4885ALDH1A1 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.