SCHEMBL29272811

SCHEMBL29272811

CC(C)(C)[Si](C)(C)Oc1cccc2c1-c1ccccc1C(O)O2

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 13/20 0.46
AR P10275 2/20 0.33
KDM4E B2RXH2 2/20 0.33
BCHE P06276 1/20 0.33
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.32
NR3C2 P08235 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11106540 0.80 NR3C1 (0.68) NR3C1ARKDM4ELMNAPGR
SCHEMBL7113477 0.70 NR3C1 (0.61) NR3C1ARPGRNR3C2
SCHEMBL30556213 0.69 CA1 (0.38) ALDH1A1
SCHEMBL9042423 0.69 MAPT (0.42) KDM4EBCHELMNAMAPTNPSR1
SCHEMBL9514004 0.69 ADRA2A (0.43) KDM4ELMNAALDH1A1
SCHEMBL11110004 0.68 NR3C1 (0.55) NR3C1ARKDM4ELMNAPGR
SCHEMBL11109865 0.68 MAOB (0.45) NR3C1ARKDM4EALDH1A1
SCHEMBL20539630 0.66 POLL (0.43)
SCHEMBL29994182 0.66 POLL (0.43)
SCHEMBL3631887 0.66 POLL (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117015530-A Urolithin derivatives and methods of use thereof 范徳利亚股份公司 2023-11-07 CN disclosed