Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964163 | 0.83 | MAPT (0.61) | MAPTALDH1A1KDM4ETHRBROCK1 | |
| SCHEMBL29272890 | 0.79 | AIMP2 (0.51) | MAPTALDH1A1KDM4ETHRBROCK1 | |
| SCHEMBL397852 | 0.74 | CFTR (0.66) | MAPTALDH1A1ROCK1KMT2AMEN1 | |
| SCHEMBL23054879 | 0.73 | HDAC1 (0.49) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL30964171 | 0.73 | MAPT (0.80) | MAPTALDH1A1KDM4EAIMP2RAB9A | |
| SCHEMBL22500323 | 0.73 | MAPT (0.70) | MAPTALDH1A1KDM4EROCK1AIMP2 | |
| SCHEMBL22500324 | 0.73 | MAPT (0.70) | MAPTALDH1A1KDM4EROCK1AIMP2 | |
| SCHEMBL30964188 | 0.73 | MAPT (0.70) | MAPTALDH1A1KDM4EROCK1AIMP2 | |
| SCHEMBL22924024 | 0.71 | CSF1R (0.41) | MAPTALDH1A1KDM4EROCK1CASP3 | |
| SCHEMBL13044616 | 0.70 | RAB9A (0.68) | MAPTALDH1A1KDM4ECASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874361-A | Novel compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2021-12-31 | — | — | CN | claimed |
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | disclosed |
| CN-113874361-A | Novel compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2021-12-31 | — | — | CN | disclosed |