Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272865 | 0.80 | MMP9 (0.54) | MAPTMMP9HDAC1 | |
| SCHEMBL29272866 | 0.80 | MMP9 (0.54) | MAPTMMP9HDAC1 | |
| SCHEMBL22500396 | 0.78 | MMP9 (0.68) | MMP9 | |
| SCHEMBL22500397 | 0.78 | MMP9 (0.68) | MMP9 | |
| P-Toluenesulfonamide SCHEMBL29272935 | 0.77 | ALDH1A1 (0.65) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL12371556 | 0.72 | MAPT (0.78) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL28373785 | 0.72 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| P-Toluenesulfonamide SCHEMBL29272949 | 0.72 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1LMNA | |
| P-Toluenesulfonamide SCHEMBL29272927 | 0.72 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7847028 | 0.71 | MAPT (0.80) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | disclosed |