Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925298 | 0.75 | CA12 (0.37) | CA12CA9MAPTTSHRKMT2A | |
| SCHEMBL28516402 | 0.70 | CA12 (0.57) | CA12CA9CA1HSD11B1RAB9A | |
| SCHEMBL4697449 | 0.70 | CA12 (0.38) | CA12CA9MAPTCA1HSD11B1 | |
| SCHEMBL12292101 | 0.65 | KDM4E (0.46) | CA12CA9CA1KMT2ATDP1 | |
| SCHEMBL9821407 | 0.64 | CA12 (0.52) | CA12CA9MAPTCA1RAB9A | |
| SCHEMBL12292200 | 0.63 | CA12 (0.39) | CA12CA9MAPTCA1HSD11B1 | |
| SCHEMBL1172438 | 0.61 | CA12 (1.00) | CA12CA9CA1KMT2ATDP1 | |
| SCHEMBL30527996 | 0.61 | CA12 (1.00) | CA12CA9CA1KMT2ATDP1 | |
| SCHEMBL21881930 | 0.59 | AKT2 (0.43) | MAPTRAB9AKMT2AALDH1A1 | |
| SCHEMBL31658296 | 0.59 | CA12 (0.46) | CA12CA9MAPTHSD11B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940849-B1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-2062476-A1 | Insecticide compositions containing 2-cyano(het)-aryl sulfonamide compounds and their isomeric forms with improved activity | Bayer CropScience AG (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009056229-A1 | INSECTICIDAL COMPOSITIONS OF 2-CYANO(HET)-ARYLSULPHONAMIDE COMPOUNDS AND THEIR ISOMERIC FORMS WITH IMPROVED ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | WO | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| EP-1940849-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | IPO5, PIR, ACHE | CA12 4389/4885CA9 3102/4885MAPT 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.