Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 13/20 | 0.52 |
| ▸ | CA9 | Q16790 | 13/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516402 | 0.70 | CA12 (0.57) | CA12CA9CA1RAB9AGAA | |
| SCHEMBL1172438 | 0.69 | CA12 (1.00) | CA12CA9CA1GAACA2 | |
| SCHEMBL30527996 | 0.69 | CA12 (1.00) | CA12CA9CA1GAACA2 | |
| SCHEMBL31455616 | 0.68 | CA12 (1.00) | CA12CA9CA1RAB9ACA2 | |
| SCHEMBL31455596 | 0.67 | CA12 (0.80) | CA12CA9CA1GAACA2 | |
| SCHEMBL6242464 | 0.66 | CA12 (0.68) | CA12CA9CA1RAB9AGAA | |
| SCHEMBL7314445 | 0.66 | CA12 (0.68) | CA12CA9CA1RAB9AGAA | |
| SCHEMBL7281068 | 0.66 | CA12 (0.68) | CA12CA9CA1RAB9AGAA | |
| SCHEMBL19286604 | 0.65 | TSHR (0.53) | RAB9AMAPTGAABRD4 | |
| Ammonia Solution, Strong SCHEMBL27564485 | 0.64 | CA12 (0.47) | CA12CA9CA1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999426-A | Preparation of 4-azasaccharines | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4889933-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0308371-A1 | 4-Aza-saccharines, 4-aza-dihydro- or -tetrahydrosaccharines and process for their preparation | CIBA-GEIGY AG (CH) | 1989-03-22 | — | — | EP | disclosed |