Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 6/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912421 | 0.85 | RAF1 (0.51) | RAF1MAPK14MAPTMAPK13MAPK12 | |
| SCHEMBL10264961 | 0.82 | RAF1 (0.40) | RAF1MAPK14MAPTKMT2AHSD17B10 | |
| SCHEMBL281723 | 0.81 | RAF1 (0.42) | NOTUMRAF1MAPK14MAPTKMT2A | |
| SCHEMBL4062812 | 0.80 | MAPT (0.42) | NOTUMRAF1MAPK14MAPTKMT2A | |
| SCHEMBL24212419 | 0.80 | L3MBTL1 (0.46) | NOTUMRAF1MAPK14MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11007849 | 0.79 | IKBKB (0.51) | NOTUMRAF1MAPK14MAPTKMT2A | |
| SCHEMBL11014523 | 0.78 | MAPT (0.43) | NOTUMRAF1MAPK14MAPTKDM4E | |
| SCHEMBL319034 | 0.77 | GSK3B (0.53) | NOTUMMAPTKMT2AHSD17B10TSHR | |
| SCHEMBL1969132 | 0.76 | KMT2A (0.51) | NOTUMRAF1MAPK14MAPTKMT2A | |
| SCHEMBL12272176 | 0.75 | HSD17B10 (0.44) | NOTUMRAF1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024441-A | MAT2A inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-11-10 | — | — | CN | disclosed |