SCHEMBL29274243

SCHEMBL29274243

O=C1C=CC(=O)C(c2cccc(Cl)c2Cl)=C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.54
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
HSD17B3 P37058 1/20 0.43
PTPRC P08575 2/20 0.41
NOTUM Q6P988 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
RECQL P46063 1/20 0.39
CCR6 P51684 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
MCL1 Q07820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10877387 0.85 PTPN11 (0.62) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL8976573 0.79 MAOA (0.50) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL31189139 0.78 MAOA (0.64) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL29241865 0.78 MAOA (0.64) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL26614363 0.74 PTPN11 (0.64) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL27976731 0.73 PTPN11 (0.45) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL27750365 0.73 PTPN11 (0.45) PTPN11MAOAMAOBHSD17B3CCR6
SCHEMBL28580646 0.72 MAOA (0.52) PTPN11MAOAMAOBHSD17B3PTPRC
SCHEMBL28961168 0.70 MAOA (0.46) PTPN11MAOAMAOBHSD17B3MEN1
SCHEMBL8678070 0.70 PTPN11 (1.00) PTPN11MAOAMAOBHSD17B3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117083320-A Resin, resin composition, coating liquid composition, film, coated film, electrophotographic photoreceptor, insulating material, molded article, electronic device, and method for producing resin 出光兴产株式会社 2023-11-17 CN disclosed
CN-114276531-B Bischloroformate composition and its preparation method, polycarbonate resin and its preparation method, electrophotographic photoreceptor and electrophotographic device 出光兴产株式会社 2023-10-20 CN disclosed