Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131913 | 1.00 | BTK (0.40) | BTKMEN1GFERKMT2AHCRTR2 | |
| SCHEMBL27224460 | 0.90 | BTK (0.45) | BTKHCRTR2HCRTR1MAPTPIK3CD | |
| SCHEMBL29276170 | 0.85 | PIK3CD (0.46) | PIK3CDJAK2JAK1 | |
| SCHEMBL29276175 | 0.85 | PIK3CD (0.46) | PIK3CDJAK2JAK1 | |
| SCHEMBL24840286 | 0.81 | CHRM2 (0.45) | MEN1GFERKMT2A | |
| SCHEMBL30801492 | 0.81 | CHRM2 (0.45) | MEN1GFERKMT2A | |
| SCHEMBL28963149 | 0.78 | HCRTR1 (0.43) | BTKHCRTR2HCRTR1MAPTPIK3CD | |
| SCHEMBL28963147 | 0.78 | HCRTR1 (0.43) | BTKHCRTR2HCRTR1MAPTPIK3CD | |
| SCHEMBL21221766 | 0.78 | PIK3CD (0.51) | PIK3CD | |
| SCHEMBL29131878 | 0.76 | IL1B (0.42) | BTKLOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118234711-A | Cyclopyridazine compounds | 尼科治疗有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116969920-A | Fused pyridazine derivative, preparation method and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |