Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276319 | 0.90 | MAPK14 (0.52) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL28599037 | 0.82 | ABL1 (0.52) | MAPK14 | |
| SCHEMBL29276339 | 0.82 | RAB9A (0.54) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29276316 | 0.80 | MEN1 (0.48) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL29276313 | 0.80 | KMT2A (0.46) | MAPTNPC1RAB9ASMN1; SMN2MAPK14 | |
| SCHEMBL29276334 | 0.79 | ALDH1A1 (0.55) | MAPTRAB9AMAPK1SMN1; SMN2MAPK14 | |
| SCHEMBL30362399 | 0.78 | F2 (0.63) | NPC1RAB9ASMN1; SMN2MAPK14F2 | |
| SCHEMBL14637157 | 0.78 | F2 (0.63) | NPC1RAB9ASMN1; SMN2MAPK14F2 | |
| SCHEMBL29276307 | 0.78 | MAPK10 (0.53) | MAPK1SMN1; SMN2MAPK14KMT2AALDH1A1 | |
| SCHEMBL29276320 | 0.78 | RIOK2 (0.48) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143097-A | Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-12-01 | — | — | CN | disclosed |