Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276742 | 0.84 | LMNA (0.61) | LMNAXBP1FAAHMAPK1FFAR2 | |
| SCHEMBL29276746 | 0.82 | LMNA (0.58) | LMNAXBP1FAAHMAPK1MAPT | |
| SCHEMBL29276744 | 0.81 | KMT2A (0.58) | LMNAXBP1FAAHMAPK1RAB9A | |
| SCHEMBL29276748 | 0.80 | ALDH1A1 (0.57) | LMNAMAPK1MAPTSMN1; SMN2TP53 | |
| SCHEMBL31006098 | 0.79 | MRE11 (0.61) | LMNAXBP1FAAHMAPTCRHBP | |
| SCHEMBL29276757 | 0.79 | MAPT (0.64) | LMNAXBP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL29276771 | 0.79 | MRE11 (0.61) | LMNAXBP1FAAHMAPTCRHBP | |
| SCHEMBL31006082 | 0.78 | MEN1 (0.58) | LMNAXBP1POLBRAB9ANPC1 | |
| SCHEMBL29276756 | 0.78 | MEN1 (0.58) | LMNAXBP1POLBRAB9ANPC1 | |
| SCHEMBL29276750 | 0.78 | LMNA (0.53) | LMNAXBP1FAAHMAPK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344304-A | Ibuprofen derivative and preparation method and application thereof | 华南农业大学 | 2024-07-16 | — | — | CN | disclosed |