SCHEMBL29277409

SCHEMBL29277409

CN(C)CCCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.67
CYP2D6 P10635 8/20 0.61
HTR1A P08908 7/20 0.61
CYP1A2 P05177 7/20 0.61
SLC6A4 P31645 6/20 0.61
LMNA P02545 6/20 0.61
MAPT P10636 6/20 0.61
DRD2 P14416 6/20 0.61
CHRM2 P08172 5/20 0.61
DRD1 P21728 5/20 0.61
DRD3 P35462 5/20 0.61
HTR2A P28223 5/20 0.61
HRH1 P35367 5/20 0.61
HTR6 P50406 5/20 0.61
SMPD1 P17405 4/20 0.61
SLC22A1 O15245 4/20 0.61
CHRM4 P08173 4/20 0.61
CHRM5 P08912 4/20 0.61
CHRM1 P11229 4/20 0.61
ADRA2B P18089 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30718485 1.00 SIGMAR1 (0.67) SIGMAR1CYP2D6HTR1ACYP1A2SLC6A4
SCHEMBL30718464 0.89 KDM1A (0.59) SIGMAR1CYP2D6HTR1ACYP1A2SLC6A4
SCHEMBL29277400 0.89 KDM1A (0.59) SIGMAR1CYP2D6HTR1ACYP1A2SLC6A4
SCHEMBL9419633 0.83 PIM1 (0.71) SIGMAR1CYP2D6HTR1ACYP1A2SLC6A4
SCHEMBL8211943 0.82 KMT2A (0.59) SIGMAR1CYP2D6HTR1ACYP1A2SLC6A4
SCHEMBL29875831 0.80 SIGMAR1 (0.55) SIGMAR1CYP2D6CYP1A2MAPTDRD2
SCHEMBL8666818 0.80 SIGMAR1 (0.55) SIGMAR1CYP2D6CYP1A2MAPTDRD2
SCHEMBL29759104 0.80 SIGMAR1 (0.55) SIGMAR1CYP2D6CYP1A2MAPTDRD2
SCHEMBL9419622 0.79 PIM1 (0.78) SIGMAR1HTR1ASLC6A4CHRM2DRD1
SCHEMBL5953850 0.79 MEN1 (0.55) SIGMAR1MAPTSMPD1ALDH1A1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285481-A Positive electrode active electrolyte based on phenoxazine quaternary ammonium salt and water system all-organic flow battery thereof 常州大学 2023-12-26 CN disclosed