Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419633 | 0.95 | PIM1 (0.71) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL29767032 | 0.88 | MEN1 (1.00) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL2269389 | 0.88 | MEN1 (1.00) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1559590 | 0.87 | MEN1 (0.98) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29358850 | 0.87 | MEN1 (0.98) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL15496911 | 0.87 | MEN1 (0.98) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL8211943 | 0.84 | KMT2A (0.59) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL6106184 | 0.84 | MEN1 (0.93) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL5953850 | 0.82 | MEN1 (0.55) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL13305235 | 0.81 | MEN1 (0.65) | PIM1MEN1KMT2ATDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108697735-A | Method for preparing cells for adoptive T cell therapy | 希望之城公司 | 2018-10-23 | — | — | CN | claimed |
| US-5371081-A | Useful in potentiating the cytotoxic effect of chemotherapeutic agents | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 1994-12-06 | — | — | US | claimed |
| WO-1993003729-A1 | N-SUBSTITUTED PHENOXAZINES FOR TREATING MULTIDRUG RESISTANT CANCER CELLS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | claimed |
| CN-117425476-A | Boric acid compounds, compositions and methods | 塔夫茨大学的受托人 | 2024-01-19 | — | — | CN | disclosed |
| CN-116981479-A | FAP-activated radiation therapy diagnostic method and use relating thereto | 塔夫茨大学信托人 | 2023-10-31 | — | — | CN | disclosed |
| CN-115697413-A | Radiopharmaceuticals and imaging agents targeting FAP and uses related thereto | 塔夫茨大学信托人 | 2023-02-03 | — | — | CN | disclosed |
| CN-108697735-A | Method for preparing cells for adoptive T cell therapy | 希望之城公司 | 2018-10-23 | — | — | CN | disclosed |
| US-20160002222-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2016-01-07 | — | — | US | disclosed |
| US-20160002222-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2016-01-07 | — | — | US | disclosed |
| US-9073916-B2 | Prodrug forms of kinase inhibitors and their use in therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2015-07-07 | — | — | US | disclosed |
| US-9073916-B2 | Prodrug forms of kinase inhibitors and their use in therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2015-07-07 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-03-29 | — | — | US | disclosed |
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-03-29 | — | — | US | disclosed |
| WO-2010104406-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-09-16 | — | — | WO | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| US-5371081-A | Useful in potentiating the cytotoxic effect of chemotherapeutic agents | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 1994-12-06 | — | — | US | disclosed |
| WO-1993003729-A1 | N-SUBSTITUTED PHENOXAZINES FOR TREATING MULTIDRUG RESISTANT CANCER CELLS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | NTRK3, TK1, TNNI3K | PIM1 610/4885MEN1 3882/4885KMT2A 1235/4885 |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | RCOR3, BRD3, BRPF3 | PIM1 3277/4885MEN1 1570/4885KMT2A 1143/4885 |
| US-20160002222-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | NTRK3, TK1, TNNI3K | PIM1 712/4885MEN1 3948/4885KMT2A 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.