Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401016 | 0.94 | ELANE (0.55) | ELANEF2LMNATSHRPOLB | |
| SCHEMBL5788955 | 0.93 | ELANE (0.58) | ELANEF2LMNATSHRPOLB | |
| SCHEMBL27615711 | 0.89 | ELANE (0.47) | ELANEF2LMNATSHRPOLB | |
| SCHEMBL28823439 | 0.88 | ELANE (0.47) | ELANELMNATSHRPOLBKMT2A | |
| SCHEMBL6654105 | 0.86 | TSHR (0.48) | ELANELMNATSHRPOLBTDP1 | |
| SCHEMBL28937493 | 0.85 | SLC6A3 (0.50) | ELANEF2LMNATSHRPOLB | |
| SCHEMBL1923782 | 0.81 | KCNH2 (0.43) | ELANELMNAKMT2AMEN1TP53 | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.79 | LMNA (0.70) | F2LMNATSHRPOLBKMT2A | |
| SCHEMBL52413 | 0.79 | LMNA (0.70) | F2LMNATSHRPOLBKMT2A | |
| Benzene SCHEMBL27793442 | 0.79 | LMNA (0.70) | F2LMNATSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |