Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540857 | 0.78 | AOC1 (0.53) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL6871548 | 0.77 | — | — | |
| SCHEMBL16884493 | 0.76 | AOC1 (0.56) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL29376653 | 0.76 | AOC1 (0.56) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL5768195 | 0.76 | AOC1 (0.51) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL26240072 | 0.76 | AOC1 (0.51) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL19766580 | 0.73 | AOC1 (0.58) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL23792402 | 0.73 | AOC1 (0.57) | AOC1AOC3LATS1LATS2HIPK2 | |
| SCHEMBL21621161 | 0.73 | AOC1 (0.49) | AOC1AOC3CA12CA1CA2 | |
| SCHEMBL30068379 | 0.73 | AOC1 (0.49) | AOC1AOC3LATS1LATS2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |