Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068360 | 0.79 | KDM4C (0.47) | AOC1AOC3KDM4CLATS1LATS2 | |
| SCHEMBL21540857 | 0.75 | AOC1 (0.53) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL3645303 | 0.74 | AOC1 (0.49) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL29376653 | 0.73 | AOC1 (0.56) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL5768195 | 0.73 | AOC1 (0.51) | AOC1AOC3HIPK2LATS1LATS2 | |
| SCHEMBL16884493 | 0.73 | AOC1 (0.56) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL29277495 | 0.73 | AOC1 (0.51) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL26240072 | 0.73 | AOC1 (0.51) | AOC1AOC3HIPK2KDM4CLATS1 | |
| SCHEMBL15981404 | 0.72 | IDO1 (0.46) | IDO1LMNA | |
| SCHEMBL30545176 | 0.71 | KDM4C (0.54) | AOC1AOC3HIPK2KDM4CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335381-A | Bifunctional degradants of interleukin-1 receptor-associated kinase and therapeutic uses thereof | 新锐思生物制药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |