SCHEMBL2927779

SCHEMBL2927779

CCC(C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(C)CC)C3=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
TERT O14746 5/20 0.40
PIN1 Q13526 1/20 0.40
PIN4 Q9Y237 1/20 0.40
KDM4E B2RXH2 4/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36
RGS12 O14924 1/20 0.36
PABPC1 P11940 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18592641 1.00 TDP1 (0.46) TDP1TERTPIN1PIN4KDM4E
SCHEMBL18592639 1.00 TDP1 (0.46) TDP1TERTPIN1PIN4KDM4E
SCHEMBL18592640 1.00 TDP1 (0.46) TDP1TERTPIN1PIN4KDM4E
SCHEMBL8480624 0.93 TERT (0.46) TDP1TERTPIN1PIN4KDM4E
SCHEMBL11938187 0.93 PRMT1 (0.41) TDP1TERTPIN1PIN4KDM4E
SCHEMBL13923574 0.85 TDP1 (0.46) TDP1KDM4EKMT2AGAACASP1
SCHEMBL13923582 0.84 TDP1 (0.45) TDP1KDM4EKMT2AGAACASP1
SCHEMBL12386897 0.83 CYP1B1 (0.59) TDP1KDM4EKMT2AGAACASP1
SCHEMBL6127956 0.83 TDP1 (0.65) TDP1GAANPC1ALDH1A1LMNA
SCHEMBL29459229 0.83 TDP1 (0.65) TDP1GAANPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US disclosed
US-20220197161-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC EQUIPMENT FUJI ELECTRIC CO., LTD. (JP) 2022-06-23 US disclosed
US-11143976-B2 Photoconductor having interlayer for hole injection promotion FUJI ELECTRIC CO., LTD. (JP) 2021-10-12 US disclosed
US-11073771-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device including the same FUJI ELECTRIC CO., LTD. (JP) 2021-07-27 US disclosed
US-11036151-B2 Electrophotographic photoreceptor, method for manufacturing same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2021-06-15 US disclosed
US-10962893-B2 Photosensitive body for electrophotography, method for producing same and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2021-03-30 US disclosed
US-20210026259-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE INCLUDING THE SAME FUJI ELECTRIC CO., LTD. (JP) 2021-01-28 US disclosed
US-20200225594-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR MANUFACTURING SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2020-07-16 US disclosed
US-20200142328-A1 PHOTOCONDUCTOR HAVING INTERLAYER FOR HOLE INJECTION PROMOTION FUJI ELECTRIC CO., LTD. (JP) 2020-05-07 US disclosed
US-8404705-B2 Naphthalene amidine imides BASF SE (DE) 2013-03-26 US disclosed
EP-1907484-B1 NAPHTHALENE AMIDINE IMIDES BASF SE (DE) 2010-09-29 EP disclosed
US-20100202984-A1 Naphthalene amidine imides BASF SE (DE) 2010-08-12 US disclosed
US-5886183-A Naphthalenelactamimide fluorescence dyes CIBA SPECIALTY CHEMICALS CORPORATOIN 1999-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100202984-A1 Naphthalene amidine imides NES, TXN2, NAT1 TDP1 3047/4885TERT 251/4885PIN1 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.